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Table 2 Clinical differences in pediatric CKD patients with and without left ventricular diastolic dysfunction

From: Left-ventricular diastolic dysfunction in Korean children with chronic kidney disease: data from the KNOW-Ped CKD study

Variable Patients with left ventricular diastolic dysfunction (n = 11) Patients without left ventricular diastolic dysfunction (n = 233) P value
Age, median (full range) 7.6 (0.5–13.0) 11.4 (0.3–17.9) 0.037
Male/Female 6/5 162/71 0.325
Chronic kidney disease stage
 I 4 (36.4) 41 (17.6)  
 II 3 (27.3) 44 (18.9)  
 III 2 (18.2) 83 (35.6)  
 IV 2 (18.2) 43 (18.5)  
 V 22 (9.4)  
Height Z-score −1.2 ± 1.0 −0.8 ± 1.6 0.445
Weight Z-score −1.1 ± 1.1 −0.8 ± 1.8 0.332
Body mass index Z-score −0.3 ± 1.2 −0.3 ± 1.4 0.861
Estimated glomerular filtration rate (ml/min/1.73 m2) 76.7 ± 46.0 56.5 ± 37.7 0.117
Hypertension 6 (66.7) 151 (71.6) 0.718
Hemoglobin (g/dL) 11.1 ± 1.8 12.4 ± 1.8 0.015
Transferrin Saturation (%) 27.6 ± 21.1 27.8 ± 13.0 0.589
Serum albumin (g/dL) 4.1 ± 0.4 4.1 ± 0.6 0.353
Serum Ca (mg/dL) 9.2 ± 0.5 9.5 ± 0.7 0.062
Serum P (mg/dL) 4.8 ± 0.5 4.8 ± 0.9 0.944
Ca x P (mg2/dL2) 43.9 ± 5.4 45.5 ± 8.5 0.456
Serum tCO2 (mmol/L) 23.3 ± 3.8 22.5 ± 3.5 0.715
Total cholesterol (mg/dL) 154.3 ± 20.7 184.5 ± 70.4 0.054
Serum low-density lipoprotein cholesterol (mg/dL) 95.0 ± 17.2 106.1 ± 63.5 0.888
Serum high-density lipoprotein cholesterol (mg/dL) 46.3 ± 11.9 54.4 ± 15.0 0.077
Serum triglyceride (mg/dL) 108.6 ± 37.5 153.5 ± 158.9 0.347
Intact parathyroid hormone (pg/mL) 49.8 (17.1–243.0) 55.3 (5.8–1244.0) 0.926
25 (OH) vitamin D3 (ng/mL) 26.0 ± 17.3 21.1 ± 9.2 0.452
Tubular reabsorption of phosphate (%) 90.5 ± 8.3 77.6 ± 13.7 0.009
Left ventricular mass index (g/m2.7) 48.8 ± 14.9 36.5 ± 12.7 0.002
left ventricular wall thickness z-score 1.4 ± 3.7 −3.1 ± 6.3 0.008
  1. Data are presented as the mean ± standard deviation, as the median with the full range given in the parentheses, or as the number of patients with the percentage given in parentheses