From: Safely reducing haemodialysis frequency during the COVID-19 pandemic
| Twice weekly HD (n = 166) | Thrice weekly HD (n = 236) | P value | |
|---|---|---|---|
| Age (years) | 65.0 [54.8–74.3] | 59.0 [49.0–71.0] | < 0.001 |
| Sex– Male (%) | 107 (64.5) | 154 (65.3) | 0.870 |
| Ethnicity - White British (%) | 110 (66.3) | 167 (70.8) | 0.339 |
| Pre HD weight (Kg)a | 73.5 [62.0–85.3] | 76.2 [64.2–91.4] | 0.038 |
| BMIb | 25.8 [22.9–29.4] | 27.5 [23.3–31.6] | 0.050 |
| Last URR (%)c | 71.1 [65.4–75.5] | 69.3 [63.1–74.4] | 0.009 |
| Corrected Calciumd (mmol/L) | 2.36 ± 0.18 | 2.34 ± 0.17 | 0.283 |
| Phosphatee (mmol/L) | 1.56 [1.27–1.89] | 1.68 [1.33–2.07] | 0.023 |
| Parathyroid Hormonef (pmol/L) | 26.9 [12.5–56.8] | 28.9 [13.2–51.9] | 0.361 |
| Haemoglobing (g/L) | 107 ± 16.1 | 107 ± 17.6 | 0.873 |
| Potassiumh (mmol/L) | 4.50 [4.00–5.20] | 4.90 [3.20–5.50] | < 0.001 |
| Albumini (g/L) | 38.0 [34.1–41.0] | 38.5 [35.0–41.0] | 0.358 |
| Pre-HD average SBPj | 148 ± 21.7 | 147 ± 22.4 | 0.617 |
| Pre-HD average DBPk | 74.0 [62.3–84.8] | 77.5 [67.0–88.0] | 0.082 |
| Post-HD average SBPl | 139 [126–154] | 137 [121–156] | 0.980 |
| Post-HD average DBPm | 72.0 [63.0–80.0] | 71.5 [63.8–83.3] | 0.584 |
| Average UFn (L) | 1.40 [1.00–2.00] | 2.00 [1.50–2.70] | < 0.001 |
| Anuric Statuso (n) | 16 | N/A | |
| Dialysis Vintage (months) | 21 (6.3–14.5) | 29.5 (11.9–261) | 0.013 |
| Primary Renal Disease | |||
| Diabetic Nephropathy (%) | 51 (30.7) | 81 (34.3) | 0.450 |
| Hypertensive/Renovascular disease (%) | 27 (16.3) | 30 (12.7) | 0.314 |
| Glomerulonephritis (%) | 21 (12.7) | 31 (13.1) | 0.886 |
| ADPKD (%) | 15 (9.0) | 13 (5.5) | 0.172 |
| Urological (%) | 13 (7.8) | 24 (10.2) | 0.425 |
| Pyelonephritis (%) | 3 (1.8) | 11 (4.7) | 0.125 |
| ANCA-associated vasculitis (%) | 4 (2.4) | 5 (2.1) | 0.847 |
| Other (%) | 17 (10.2) | 16 (6.8) | 0.214 |
| Unknown (%) | 15 (9.0) | 25 (10.6) | 0.610 |
| Comorbidity | |||
| Ischaemic heart disease (%) | 25 (15.1) | 40 (17.0) | 0.613 |
| Heart Failure (%) | 5 (3.0) | 18 (7.6) | 0.049 |
| CVA (%) | 16 (9.7) | 35 (14.8) | 0.124 |
| Diabetes Mellitus (%) | 62 (37.4) | 101 (42.8) | 0.274 |
| ACEi (%) | 30 (18.1) | 46 (19.5) | 0.721 |
| ARB (%) | 19 (11.5) | 32 (13.6) | 0.532 |