You are viewing the site in preview mode

Skip to main content

Table 3 Baseline clinical and laboratorial characteristics for twice weekly patients

From: Safely reducing haemodialysis frequency during the COVID-19 pandemic

  Completed full trial (n = 113) Failed twice weekly dialysis (n = 28) P value
Age (years) 63.1 ± 14.2 65.1 ± 14.7 0.5257
Sex– Male (%) 76 (67.3) 12 (52.2) 0.1686
Ethnicity - White British (%) 78 (69.0) 17 (73.9) 0.6420
Pre HD weight (Kg) 73.5 [62.0–83.2] 76.4 [71.6–86.6] 0.1545
BMI 25.8 [22.7–28.8] 28.2 [24.5–32.9] 0.0395
Last URR (%)a 70.6 [66.2–76.7] 72.5 [69.3–74.3] 0.8383
Corrected Calcium (mmol/L) 2.35 ± 0.18 2.36 ± 0.18 0.7784
Phosphate (mmol/L) 1.55 ± 0.44 1.68 ± 0.56 0.2030
Parathyroid Hormoneb (pmol/L) 28.3 [12.0–59.2] 25.7 [11.6–36.5] 0.3732
Haemoglobin (g/L) 108 ± 15.5 101 ± 19.9 0.0940
Potassium (mmol/L) 4.52 ± 0.77 4.76 ± 0.84 0.1792
Albumin (g/L) 38.3 ± 4.65 35.0 [32.7–40.0] 0.0557
Pre-HD average SBP 148 ± 21.3 149 ± 21.0 0.8362
Pre-HD average DBP 73.9 ± 15.4 74.8 ± 13.1 0.7889
Post-HD average SBPc 138 [125–155] 134 [125–150] 0.5987
Post-HD average DBPd 71.0 [62.5–80.0] 72.0 [64.0–79.0] 0.8243
Average UF (L) 1.30 [1.00–2.00] 2.20 [1.40–2.60] 0.0007
Dialysis Vintage (months) 19.2 (5.3–45.2) 20.7 (8.0–61.4) 0.5270
Primary Renal Disease
 Diabetic Nephropathy (%) 35 (31.0) 9 (39.1) 0.4508
 Hypertensive/Renovascular disease (%) 20 (17.7) 4 (17.4) 0.9727
 Glomerulonephritis (%) 13 (11.5) 5 (21.7) 0.1897
 ADPKD (%) 11 (9.7) 2 (8.7) 0.8821
 Urological (%) 9 (8.0) 1 (4.3) 0.5375
 Pyelonephritis (%) 2 (1.8) 0 (0.0) 0.5183
 ANCA-associated vasculitis (%) 2 (1.8) 0 (0.0) 0.5183
 Other (%) 11 (9.7) 0 (0.0) 0.1207
 Unknown (%) 10 (8.8) 2 (8.7) 0.9877
Comorbidity
 Ischaemic heart disease (%) 21 (18.6) 2 (8.7) 0.2502
 Heart Failure (%) 4 (3.5) 1 (4.3) 0.8523
 CVA (%) 8 (7.1) 6 (26.1) 0.0065
 Diabetes Mellitus (%) 48 (42.5) 10 (43.5) 0.9298
 ACEi (%) 24 (21.2) 5 (21.7) 0.9576
 ARB (%) 18 (15.9) 0 (0.0) 0.0408
  1. Results are expressed as mean ± SD, median [IQR; interquartile range] or n (%).p-value calculated using unpaired T test for parametric data and Mann-Whitney U Test for non-parametric data. Categorical variables were analysed by Chi-square test. Abbreviations: BMI – Body Mass Index, HD – Haemodialysis, SBP – Systolic Blood Pressure, DBP – Diastolic Blood Pressure, URR – Urea Reduction Ratio, ADPKD – Autosomal Dominant Polycystic Kidney Disease, CVA – Cerebrovascular event, ACEi– Angiotensin converting enzyme inhibitor, ARB - Angiotensin receptor blocker. amissing for 13 patients in completed full twice weekly group and 5 patients in failed twice weekly group. bmissing for 1 patient in failed twice weekly group. cmissing for 4 patients in completed full twice weekly group. dmissing for 4 patients in completed full twice weekly group