From: Safely reducing haemodialysis frequency during the COVID-19 pandemic
| Completed full trial (n = 113) | Failed twice weekly dialysis (n = 28) | P value | |
|---|---|---|---|
| Age (years) | 63.1 ± 14.2 | 65.1 ± 14.7 | 0.5257 |
| Sex– Male (%) | 76 (67.3) | 12 (52.2) | 0.1686 |
| Ethnicity - White British (%) | 78 (69.0) | 17 (73.9) | 0.6420 |
| Pre HD weight (Kg) | 73.5 [62.0–83.2] | 76.4 [71.6–86.6] | 0.1545 |
| BMI | 25.8 [22.7–28.8] | 28.2 [24.5–32.9] | 0.0395 |
| Last URR (%)a | 70.6 [66.2–76.7] | 72.5 [69.3–74.3] | 0.8383 |
| Corrected Calcium (mmol/L) | 2.35 ± 0.18 | 2.36 ± 0.18 | 0.7784 |
| Phosphate (mmol/L) | 1.55 ± 0.44 | 1.68 ± 0.56 | 0.2030 |
| Parathyroid Hormoneb (pmol/L) | 28.3 [12.0–59.2] | 25.7 [11.6–36.5] | 0.3732 |
| Haemoglobin (g/L) | 108 ± 15.5 | 101 ± 19.9 | 0.0940 |
| Potassium (mmol/L) | 4.52 ± 0.77 | 4.76 ± 0.84 | 0.1792 |
| Albumin (g/L) | 38.3 ± 4.65 | 35.0 [32.7–40.0] | 0.0557 |
| Pre-HD average SBP | 148 ± 21.3 | 149 ± 21.0 | 0.8362 |
| Pre-HD average DBP | 73.9 ± 15.4 | 74.8 ± 13.1 | 0.7889 |
| Post-HD average SBPc | 138 [125–155] | 134 [125–150] | 0.5987 |
| Post-HD average DBPd | 71.0 [62.5–80.0] | 72.0 [64.0–79.0] | 0.8243 |
| Average UF (L) | 1.30 [1.00–2.00] | 2.20 [1.40–2.60] | 0.0007 |
| Dialysis Vintage (months) | 19.2 (5.3–45.2) | 20.7 (8.0–61.4) | 0.5270 |
| Primary Renal Disease | |||
| Diabetic Nephropathy (%) | 35 (31.0) | 9 (39.1) | 0.4508 |
| Hypertensive/Renovascular disease (%) | 20 (17.7) | 4 (17.4) | 0.9727 |
| Glomerulonephritis (%) | 13 (11.5) | 5 (21.7) | 0.1897 |
| ADPKD (%) | 11 (9.7) | 2 (8.7) | 0.8821 |
| Urological (%) | 9 (8.0) | 1 (4.3) | 0.5375 |
| Pyelonephritis (%) | 2 (1.8) | 0 (0.0) | 0.5183 |
| ANCA-associated vasculitis (%) | 2 (1.8) | 0 (0.0) | 0.5183 |
| Other (%) | 11 (9.7) | 0 (0.0) | 0.1207 |
| Unknown (%) | 10 (8.8) | 2 (8.7) | 0.9877 |
| Comorbidity | |||
| Ischaemic heart disease (%) | 21 (18.6) | 2 (8.7) | 0.2502 |
| Heart Failure (%) | 4 (3.5) | 1 (4.3) | 0.8523 |
| CVA (%) | 8 (7.1) | 6 (26.1) | 0.0065 |
| Diabetes Mellitus (%) | 48 (42.5) | 10 (43.5) | 0.9298 |
| ACEi (%) | 24 (21.2) | 5 (21.7) | 0.9576 |
| ARB (%) | 18 (15.9) | 0 (0.0) | 0.0408 |